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Lapatinib paʻu (231277-92-2)

fua faatatau:
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SKU: 231277-92-2. Category:

AASraw faʻatasi ma le faʻasologa ma le gaosiga gafatia mai le gram i le faʻatonuga tele o le lapatinib paʻu (231277-92-2), i lalo o le CGMP tulafono faatonutonu ma le siakiina lelei o le faʻaleleia o le tino.

Faamatalaga oloa

Lapatinib paʻu video


Lapatinib paʻu Uiga masani

igoa: Lapatinib paʻu
CAS: 231277-92-2
Polokalame Molecular: C29H26ClFN4O4S
Taumaʻa Masele: 581.05
Melt Point: 136-140 ° C
Teu o le Teuina: Failautusi
Valivali: Paʻepaʻe paʻepaʻe pe paʻe paʻepaʻe


Laʻau Lapatinib Raw i le Cycle Antineoplastic Agent cycle

Igoa

Igoa ole Igoa ole: Lapatinib powder (PA PA)
Igoa Faʻailoga: Tykerb

Faʻaaogaina o le Lapatinib Raw Lapinib

Lapatinib powder is a medicinal medicine used with other medicine (capcitabine) e togafitia ai tagata e maua i le kanesa o le susu lea ua salalau atu i isi vaega o le tino o HER2 positive (o tumema e maua ai le tele o se porotini e taʻua o le tagata e maua mai le epidermal grow factor receptor-2) , ma ua uma ona iai nisi togafitiga o le kanesa o le susu.

Lapatinib paʻu o loʻo faʻaaogaina foʻi ma se ituaiga o vailaʻau e taʻua o le letrozole mo le togafitiga o fafine meli meli, o loʻo maua ai le siama o le hormone positive, HER2 o le kanesa o le susu gasegase o loʻo faʻaalia ai le hormonal therapy.

Lapatinib powder is a medicinal medicine used to treat cancer cancer. E faʻaaogaina faʻatasi ma isi vailaʻau e togafitia ai se ituaiga o kanesa o le susu lea ua salalau atu i isi vaega o le tino ma e leʻi tali atu i isi togafitiga o le kanesa.

O le lapatinib o le paʻu o se vaega o vailaʻau e taʻua o le inaseta kinase lea e galue e ala i le taofia o le gaioiga o se polotini faapitoa lea e faʻaalia ai potu o le kanesa e faʻateleina ai.

O lenei vailaʻau e sau i le laulau ma faʻaaogaina i aso taʻitasi i luga o se manava gaogao.

O aʻafiaga lautele masani o le lapatinib paʻu e aofia ai le mumu, lima tiga ma vae, manava, vevela, ma le gaioiga.

O le a le metotia o le lapatinib paʻu

Faigata masani mo le Kanesa o le susu

-HAUSAGA-LELEI METASTATIC BREAST CANCER (faʻapipiʻi ma le capecitabine): 2 mg faʻatasi i lea aso ma lea aso i Aso 1250 i le 1 faʻaauau i le toe faia o le 21 aso seia oʻo i le faʻamaʻi poʻo le le taliaina o le faʻamaʻi.

-O LE MAUA MAUA MAUA, LE HER2-POSITIVE METASTATIC BREAST CANCER (faʻatasi ma le letrozole): 1500 mg faʻasalalauga faʻatasi i lea aso ma lea aso.

faamatalaga:
- Faʻasoa le faʻamatalaga o oloa gaosi oloa mo le capecitabine ma le letrozole fautuaga fautuaina.
-HER2-lelei o le gasegase o le susu o le susu e tatau ona i ai le faʻafitauli o le maʻi i luga o trastuzumab ao le i amataina togafitiga i lenei vailaʻau faʻatasi ma le capecitabine.

Faaaogaina:
-Faʻatasi ma le faʻasologa o togafitiga mo togafitiga o gasegase o loʻo maua i le gasegase o le susu po o le gasegase o le gasegase ole tino ole HER2 ma o latou na mauaina muamua togafitiga e aofia ai se anthracycline, se taxan, ma le trastuzumab.
-Faʻatasi ma le letrozole mo le togafitiga o fafine ua maeʻa i le maeʻa mai o le susu e faʻamaonia ai le kanesa o le susu o le masini e faʻasalaina ai le HER2 o loʻo maua ai le faʻasologa o le hormonal.

Renal Dose Adjustments
Faʻamatalaga e le maua e uiga i fetuunaiga o vailaʻau; peitaʻi, o vailaʻau mo togafitiga o lenei vailaʻau e ono le aʻafia ona o le itiiti ifo nai lo le 2% o le suʻega faʻafoe ua faʻaumatia e fatugaʻo.

Faʻasologa o Faiga Faʻafefe
SAUNOAʻE TUSI I LE FUAFUAINA O LE HEPATIC IMPAIRMENT (TAMAITI FAʻAMATALAGA A / B): Faʻamaumauga e le maua.

FAʻAMATALAGA MUAMUA FAʻAMATALAGA (TAMAITI FAʻAVAE): Faʻaititia le togi:
-HER2-Cancer Canast Metastatic Positive (faatasi ai ma le capecitabine): 750 mg / aso.
-O le Tonu e Taligofie-Tonu, HER2-Positive Metastatic Breast Cancer (faʻatasi ma le letrozole): 1000 mg / aso

SEVERE HEPATOTOXICITY OCCURS I LE LUMAʻI: Taofi tumau le togafitiga.

Faʻamatalaga: O le faia o fautuaga faʻavae e faʻavae i luga o suʻesuʻega o vailaau faʻatau; e leai ni faʻamatalaga faʻamatalaga e maua.

Faʻasologa o Suiga
FAʻAMATALAGA FAʻATASI MA TULAGA CYP450 3A4 INHIBITORS MA / OR TULAGA CYP450 3A4 AOAOGA: Aloese mai le faʻamafanafana pe a mafai. O le faia o fautuaga fetuutuunai e faʻavae i luga o suʻesuʻega o vailaau mo togafitiga; e leai ni faʻamatalaga faʻamatalaga e maua.
FAʻAMATALAGA FAʻATONU MA LE CYP450 3A4 INHIBITOR: Faʻasaʻo le dose ile 500 mg / aso; faʻataga le vaitaimi o le leai o se taimi e tusa o le 1 vaiaso aʻo leʻi toe faʻaleleia le fualaau o lenei vailaʻau i le masani masani fautuaina pe a le toe faʻatagaina le inhibitor.
FAʻAMATALAGA FAʻAMATALAGA MA LE CYP450 3A4 INDUCER: Faʻasolosolo i luga o fuataga e faʻavae i luga ole toleniva; faʻaitiitia le toe foʻi atu i le masani masani fautuaina pe a fai e le toe faʻaaogaina.
-HER2-Cancer Canast Metastatic Positive (faatasi ai ma le capecitabine): Faʻateleina le oʻo i 4500 mg / aso.
-O le Tali-Positive, HER2-Positive Metastatic Breast Cancer (faʻatasi ma le letrozole): Faʻateleina le oʻo i 5500 mg / aso.

NOFOAGA 2 poʻo LĒ FAIGALUEGA LELEI EJECTION FRACTION (LVEF) PE LĒ FAʻAALIGA I LE TALAFAASOLOPITO A LE INSTITUTION: Faʻasalaga togafitiga; e mafai ona toe amata i le aofaʻi laʻititi pe a maeʻa le 2 vaiaso pe afai o le LVEF e toe maua i le masani ma le onosaʻi o le soymptomatic.
Faʻasolo i lalo Mea:
-HER2-Cancer Canast Metastatic Positive (faʻatasi ma le capecitabine): 1000 mg / aso
-O le Tonu e Taligofie-Tonu, HER2-Positive Metastatic Breast Cancer (faʻatasi ma le letrozole): 1250 mg / aso

TUSI 3 PO O LE VAEGA 1 poʻo 2 I LE FAʻAMATALAINA O MEA (faʻaleagaina i le ogaoga o le manava o le tino, 2 grade poʻo le sili atu o le vevela poʻo le vomiting, faʻaitiitia le tulaga o le faatinoga, fiva, lepsis, neutropenia, faʻamaʻi pipisi, poʻo le faʻamaʻavaina): Toe faʻaleleia i lalo ifo o le manava foia le Aʻoga 1 pe itiiti.
Faʻasolo i lalo Mea:
-HER2-O le gasegase o le gasegase o le susu o le susu (faʻatasi ma le capecitabine): 1000 mg / aso
-O le Tali-Positive, HER2-Positive Metastatic Breast Cancer Patient: 1250mg / aso
GRADE 4 DIARRHEA: Taofi tumau le togafitiga.

O ISI TOXICITIES, GRADE 2 poʻo LE SILI: E mafai ona mafaufau i le faʻagataina poʻo le faʻalavelaveina o le tuʻuina atu; e mafai ona toe amata i le masani masani fautuaina pe a faʻamalosia le faʻamaʻi i le Vasega 1 pe itiiti.
AFAI E MAUA AI LE TOXICITY: Faʻaititia le togi:
-HER2-Cancer Canast Metastatic Positive (faʻatasi ma le capecitabine): 1000 mg / aso
-O le Tali-Positive, HER2-Positive Metastatic Breast Cancer Patient: 1250mg / aso

E faapefea ona galue le paʻu lapatinib lapoʻa

Lapatinib paʻu o loʻo faʻaaogaina ma le capecitabine (Xeloda) e togafitia ai se ituaiga o le kanesa o le susu i tagata ua uma ona togafitia i isi togafitiga o le chemotherapy. Lapatinib paʻu o loʻo i totonu o se vasega o vailaau e taʻua o le inaseta kinase. E galue e ala i le taofia o le gaioiga o le palatini le talafeagai lea e faʻaalia ai lela o le kanesa e faʻateleina. E fesoasoani lenei mea e taofi pe faʻagesegese ai le salalau o sene o le kanesa

lapataʻiga

Taʻu atu i lau auʻaunaga uma soifua maloloina e te ave le laʻau o Lapatinib. E aofia ai lau fomaʻi, tausimaʻi, fomaʻi, ma fomaʻi.
Afai ei ai lou manava le fiafia, tulei i luga, vavalavave (manava manava), pe le fiaai, talatalanoa ma lau fomaʻi. Atonu ei ai auala e faʻaititia ai nei aʻafiaga itu.
Lavela (manava manava) ua tupu i le paʻu Lapatinib. O nisi taimi, o le manava manaia ua matua leaga ma ua tupu maliu. Talanoa ma lau fomaʻi.
Afai ei ai ni faʻalava vavalo (manava), talanoa ma lau fomaʻi. Aua e te taumafai e togafitia le manava e aunoa ma le siaki muamua i lau fomaʻi.
Fai siaki le galuega toto e pei ona taʻuina e le fomaʻi. Talanoa ma le fomai.
O le ae manaomia le i ai o suʻega a le fatu aʻo e ave le laʻau o Lapatinib. Talanoa ma le fomai.
Aloese mai le vine ma le sua o le vine.
Afai oe ave le digoxin, talanoa ma lau fomaʻi. Atonu e te manaʻomia le siaki lelei o lau toto aʻo e ave faʻamalosi i le lapatinib powder.
O lenei vailaʻau e mafai ona faʻaleagaina ai le pepe e leʻi fananau mai pe afai e te aveina aoe maʻitaga.
Faʻaaogā le faʻalogoina o le pepe e mafai ona e faʻatuatua e puipuia ai le maitaga aʻo e ave le laʻau o Lapatinib.
Afai oe maʻitaga pe e te maʻitaga aoe ave le laʻau o le Lapatinib, valaʻau lau fomaʻi e tauva.

Lapatinib Laupeʻa Maea

Min poloaiga 10grams.
O le suʻesuʻega i le aofaʻi masani (I totonu ole 1kg) e mafai ona lafo i 12 itula pe a uma ona totogi.
Mo se faasologa sili atu e mafai ona tuʻuina atu ile 3 aso faigaluega pe a uma le totogiina.

Lapatinib powder Marketing

Ia saunia i le lumanai.

E i ai le afaina Lapatinib La Lapatinib i Soʻo se Itū Faʻafeagai

Faatasi ai ma ona manaʻoga manaʻomia, o le lapatinib paʻu e ono mafua ai ni faʻafitauli e le manaʻomia. E ui lava e le mafai ona tutupu uma nei itu itu, pe afai latou te faia e ono manaʻomia le togafitiga faafomaʻi.

Siaki faʻatasi lau fomaʻi pe'āfai e tupu se tasi o aʻafiaga o loʻo mulimuli mai aʻo e ave le Lapatinib paʻu:

Le masani ai
Le manava pe galue malosi
faʻanoanoa
anapogi po o le faaletonu o le fatu
ogaoga manava
fusi i totonu o le pusa
le vaivai le masani ai po o le vaivai
mauagatā

Paʻu o le tino po o le manava poʻo le agavaivai
omea lanu enaena
pogisa pouliuli
faaitiitia le fiaai
fiva
ulu tīgā
sasaina poʻo le paʻu paʻu
leai se manaʻo
vevela ma le vili
fula o vae po o lalo vae
mata samasama po o le paʻu
Faʻafitauli e le o iloa
Matapeʻapeʻa, toso, tatalaina o le paʻu
tiga o le pusa
tagi
tale
tatā
faigata i le afaina
dizziness
lagona lautele o le le mautonu po o gasegase
sulu
mafutaga poʻo le tiga o muscle
vaivai po o le fulafula o laumata po o le va o mata, foliga, laugutu, po o le laulaufaiva
lanu mumu mumu, e masani lava i se fale lanu violē
mumu, mata mataga
tiga fa'a'i
soga, maʻi paʻu, po o lanu paʻepaʻe i le gutu po o laugutu
ufiufi o mea faalilolilo
O nisi aʻafiaga o le lapatinib paʻu e ono tupu e masani lava e le manaʻomia se togafitiga faafomaʻi. O nei aʻafiaga e mafai ona alu i le taimi o togafitiga ao faʻaleleia lou tino i vailaʻau. E le gata i lea, e mafai e lau fomaʻi tausi soifua maloloina ona taʻu atu ia te oe auala e puipuia ai pe faʻaititia ai nisi o nei itu. Siaki i lau fomaʻi tausi soifua maloloina pe'āfai e faʻaauauina pe aʻafia soʻo se tasi o aʻafiaga nei pe afai ei ai ni au fesili e uiga ia i latou:

Faateleina
Afe po o le manava oona
tua tiga
fusi
laugutu gutu
manava manava (agamalu)
paʻu matutu
toso
otaota
tiga i lima po o vae
mumu, fula, pe paʻu tiga
siakiina o le paʻu i lima ma vae
soga, maʻilasea, poʻo lanu paepae i laugutu, laulaufaiva, poʻo totonu o le gutu
manava le manava, ita, po o le tiga
fulafula pe afaina o le gutu
tingling o lima ma vae
faafitauli o moe


Auala e faʻatau ai le lapatinib paʻu mai AASraw

1.E faʻafesoʻotaʻi mai i matou i la matou imeli suʻesuʻega, poʻo le skypesui o le au faipisinisi (CSR).
2.E tuʻu mai ia i matou le tele o au fesili ma lau tuatusi.
3.Our CSR o le a tuʻuina atu ia te oe le upusii, taimi o totogi, numera o le suʻega, auala e tuʻuina atu ai ma le aso atofaina e taunuu ai (ETA).
4.Payment na faia ma o oloa o le a auina atu i itula 12 (Mo le faʻasalalauga i totonu ole 10kg).
5.Goods na maua ma tuuina mai ni faʻamatalaga.


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COA

COA 231277-92-2 Lapatinib paʻu AASRAW

HNMR

O matou o le Lapatinib faʻamalosia paʻu, Lapatinib elefise mo le faʻatau atu, Paʻu Raw Lapatinib (231277-92-2) hplc≥98% | AASraw R & D Reagents

Recipes

Lapatinib Malosiaga Suʻe Recipes:

Faʻatalanoaina o matou Tagata Faʻatau (CSR) mo auiliiliga, mo lau faʻamatalaga.

Faʻamatalaga & faʻamaumauga o oloa

Tykerb (231277-92-2) -O le fasiotia o le pulou pepe