Spermidine trihydrochloride efuefu - Gaosi oloa Tuuina atu
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Spermidine trihydrochloride

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Spermidine trihydrochloride efuefu o se natura polyamine gaosia mai putrescine ma decarboxylated S-adenosylmethionine (dcSAM) e spermidine synthase, o se tala autophagy inducer ma suia le lelei N-methyl-d-aspartate (NMDA). Spermidine trihydrochloride na faʻaaogaina i le fa atinoina fesuiaʻiga infrared spectroscopy (FTIR) faʻailoga ma i zeta-ono fuaina. Spermidine hydrochloride e maua lautele i le natura ma taua mo le tuputupu aʻe o aano; Faʻaaogaina o se mea faigaluega i biochemical suesuega; "O le Spermidine hydrochloride o se vaega o le polyamine, C7H22Cl3N3, o loʻo maua i ribosome ma mea ola o loʻo ola ai ma e tele ona aoga i le tino i totonu o meaola.

Faamatalaga oloa

Igoa oloa Spermidine trihydrochloride
Numera CAS 334-50-9
Faiga Faʻavae Molecular C7H22Cl3N3
Fua Faatatau o le Umi 254.6
Synonyms N- (3-Aminopropyl) -1,4-butanediamine trihydrochloride; 1,8-Diamino-4-azaoctane trihydrochloride; 1,5,10-Triazadecane trihydrochloride; S permidine.3HCl
Faʻaaliga Paʻepaʻe paʻepaʻe
Teuina ma Taulimaina Faʻamago, pogisa ma 0 - 4 C mo se taimi puʻupuʻu, pe -20 C mo se taimi umi.

 

Tusitaiala

[1] Kishi et al (1998) Spermidine, o le polyamine site agonist, faʻamalosia le manatuaina o le mafaufau na mafua mai i le poloka o hippocampal muscarinic mauaina ma mGluRs i isumu. Faiai Res. 793 311 PMID: 9630697.

[2] Munir et al (1993) Polyamines faʻataʻitaʻia le neurotoxic effects o le NMDA i vivo. Faiai Res. 616 163 PMID: 8358608.

[3] Williams et al (1989) Aʻafiaga o polyamines i le fusifusia o le [3H] -MK801 i le N-MthD.-aspartate receptor: vailaʻau faʻamaonia mo le i ai o se polyamine aloaʻia nofoaga. Mol.Pharmacol. 36 375 PMID: 2554112.

[4] Galluzzi et al (2017) Faʻatulagaina o vailaʻau moʻi o le autophagy: mafai gafatia ma faʻalavelave tumau. Nat.Rev.Drug.Discov. PMID: 28529316.

 

Tusitusiga masani

 

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